Can a cream soothe knee osteoarthritis pain?

NCT ID NCT07745387

Completed Symptom relief Sponsor: Pharmanutra S.p.a. Source: ClinicalTrials.gov ↗

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This study tests whether a cream made with cetylated fatty acids can ease knee pain and improve function in adults with osteoarthritis. Participants apply the cream or a placebo to the affected knee twice daily for 30 days. The trial measures changes in pain during walking, physical function, use of rescue medication, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: A topical cream containing cetylated fatty acids (CFA), applied to the affected knee twice daily for 30 days.
What this could lead to: If effective, this cream could offer a non-invasive, topical option to reduce knee pain and improve mobility in people with osteoarthritis.
What could go wrong: This is an early-stage trial with a modest number of participants, and the cream may not prove more effective than a placebo. As with any topical product, skin irritation is possible.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRISTIS

Contacts and locations

Locations

LLC "Altra Vita"

Tbilisi, Georgia
LLC Institute of Clinical Cardiology

Tbilisi, Georgia
LLC The First Medical Center

Tbilisi, Georgia
LLC Unica

Tbilisi, Georgia

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