Knee implant showdown: cemented vs cementless in new study

NCT ID NCT03522025

Ongoing Disease control Sponsor: Medacta International SA Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two types of knee implants for people with knee osteoarthritis: one fixed with bone cement and one without. 70 participants will be randomly assigned to receive either a cemented or cementless implant. The goal is to see which type stays better fixed in the bone over 5 years, by checking for signs of loosening on X-rays.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: unicompartmental knee prosthesis (cemented or cementless design)
What this could lead to: If successful, this could help doctors choose the best type of knee implant for patients with knee osteoarthritis, potentially improving implant longevity and reducing complications.
What could go wrong: This is a small, early-stage study with only 70 participants, so results may not apply to everyone. The main focus is on implant fixation, not on curing the disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

CHP Saint-Grégoire

Saint-Grégoire, France, 35760, France
Centre Orthéo, Espace Fauriel

Saint-Etienne, France, 42100, France
Clinique Saint Vincent de Paul

Bourgoin, France, 38300, France
Clinique du Mail

La Rochelle, France, 17000, France
Dr. Näder Helmy

Solothurn, Switzerland, 4500, Switzerland

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