New cell patch could ease knee arthritis pain without replacement

NCT ID NCT06549686

Recruiting now Disease control Sponsor: CellSeed Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This study tests whether a lab-grown sheet of human cartilage cells (CLS2901C) can improve knee function and reduce pain in people with knee osteoarthritis. About 96 adults aged 20–79 who need knee realignment surgery will receive either the cell sheet plus surgery or surgery alone. The main goal is to measure changes in pain, symptoms, daily activities, and quality of life one year after treatment.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS OF THE KNEE

Contacts and locations

Locations

Ebina General Hospital/Ebina Medical Plaza
RECRUITING

Ebina, Kanagawa, 243-0433, Japan
Juntendo University Hospital
RECRUITING

Bunkyō-Ku, Tokyo, 113-8431, Japan
Tokai University Hospital
RECRUITING

Isehara, Kanagawa, 259-1193, Japan
Yokohama City University Medical Center
RECRUITING

Yokohama, Kanagawa, 232-0024, Japan
Yokohama Minami Kyousai Hospital
RECRUITING

Yokohama, Kanagawa, 236-0037, Japan
Yokohama Sekishinkai Hospital
RECRUITING

Yokohama, Kanagawa, 230-0062, Japan

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