New combo treatment aims to ease knee pain without surgery

NCT ID NCT05286775

Completed Symptom relief Sponsor: Marta Imamura Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed trial tested whether adding medical treatments (lidocaine injections and shockwave therapy) to a knee education program could better reduce pain and improve function in people with knee osteoarthritis. 71 participants with moderate to severe knee pain were randomly assigned to either the education program alone or the education program plus the medical treatments. The study measured changes in knee function and pain at the end of treatment and three months later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lidocaine and shockwave therapy
What this could lead to: If successful, this approach could offer a non-surgical option to reduce pain and improve knee function in people with knee osteoarthritis.
What could go wrong: This is a small, completed trial with only 71 participants, so results may not apply to everyone. The treatments are short-term and may not provide lasting relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OSTEOARTHRITIS, KNEE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

osteoarthritis, knee Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

Instituto de Medicina Física e Reabilitação (IMREA-FMUSP)

São Paulo, São Paulo, 04101-300, Brazil

More trials for these conditions

Other studies related to the condition(s) this trial covers.