Brain scans may reveal best painkiller for knee arthritis
NCT ID NCT06245109
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to find out if brain-based tests can predict who will get pain relief from common knee osteoarthritis treatments. About 180 adults with knee pain will be randomly assigned to take duloxetine, celecoxib, or a placebo for 20 weeks. Researchers will use brain MRIs, knee X-rays, blood tests, and pain sensitivity checks to look for clues that predict treatment success.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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