Can less immunosuppression save kidneys after transplant?
NCT ID NCT00213590
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether giving kidney transplant patients a lower dose of the drug cyclosporine could protect their kidney function over time. 208 patients who were at least one year post-transplant and on stable medications took part. The goal was to balance preventing organ rejection while reducing drug side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cyclosporine A (reduced dose) with mycophenolate mofetil
What this could lead to
If successful, this could help kidney transplant patients maintain better kidney function with fewer side effects from immunosuppressants.
What could go wrong
This is a completed Phase 3 trial, but results may not apply to all patients. Lowering immunosuppression could increase the risk of organ rejection.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU de ROUEN
Rouen, 76031, France