AI may spot hidden kidney transplant rejection
NCT ID NCT07741552
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This study is developing an artificial intelligence (AI) system to analyze kidney biopsy images from transplant patients. The goal is to see if AI can accurately tell apart different types of rejection, measure how much damage the kidney has, and predict if rejection might come back. Researchers will use leftover biopsy samples and medical records from about 1,000 patients, with no extra procedures or costs for participants. If the AI works well, it could help doctors make more precise treatment decisions and improve long-term outcomes for kidney transplant recipients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Artificial intelligence model analyzing kidney biopsy images and clinical data
- What this could lead to
- If successful, this AI tool could help doctors more accurately diagnose kidney transplant rejection, assess its severity, and predict the risk of recurrence, potentially improving long-term transplant outcomes.
- What could go wrong
- This is an observational study using existing biopsy samples, so it won't directly test a new treatment. The AI model's accuracy and reliability need to be validated, and it may not generalize to all patient populations or clinical settings.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A simple blood test may reveal kidney damage in lupus — no biopsy needed?
- A drug given to organ donors may help kidneys work faster after transplant
- Which diuretic protects a new kidney best? a Head-to-Head trial puts furosemide and mannitol to the test
- Blood test clues could make antifungal dosing safer for transplant patients
- New Two-Step therapy aims to stop chronic kidney transplant rejection
- Smartphone app and booklet could help kidney transplant patients stick to medications