New laser mode may speed up kidney stone removal

NCT ID NCT06346483

Ongoing Symptom relief Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two laser methods for breaking up kidney and ureteral stones during surgery. One method uses standard laser pulses, the other uses a newer 'Moses 2.0' pulse mode. Researchers want to see if the newer mode reduces surgery time and improves stone clearance. About 150 adults with stones 8-20 mm will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Holmium:YAG laser with Moses 2.0 pulse modulation
What this could lead to: If successful, this could show that Moses 2.0 technology shortens surgery and laser time for kidney stone removal, leading to faster recovery.
What could go wrong: This is a small, early-stage comparison of an already approved device. The difference between techniques may be small, and results may not apply to all stone types or sizes.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis ureterolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KIDNEY STONE URETERAL STONE

Contacts and locations

Locations

Northwestern Medicine

Chicago, Illinois, 60611, United States

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