Antifungal drug explored as brain tumor treatment – study halted early

NCT ID NCT03796273

First seen Apr 03, 2026 · Last updated May 15, 2026 · Updated 8 times

Summary

This study looked at whether the antifungal drug ketoconazole could block a protein called tGLI1 in brain tumors. It included 15 adults with breast cancer that spread to the brain or with a type of brain tumor called glioma. The goal was to see if the drug could affect the tumor's growth signals before surgery. The study was stopped early, so results are limited.

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Contacts and locations

Locations

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

Conditions

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