Fiber fix? inulin may supercharge GLP-1 Weight-Loss drugs for heart health

NCT ID NCT07611552

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking inulin, a type of dietary fiber, can improve cholesterol and other heart-related risk factors in 600 overweight or obese adults who are already using GLP-1 medications (like semaglutide) for weight loss. Participants will take either 10 grams of inulin or a placebo daily for 4 months. The goal is to see if adding this simple supplement can make these popular weight-loss drugs even better for long-term heart health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

inulin (a type of dietary fiber/prebiotic)

What this could lead to

If it works, adding inulin to GLP-1 medications could improve cholesterol and triglyceride levels, making weight-loss treatments better for heart health.

What could go wrong

This is an early-stage supplement study, not a drug trial. The effect may be small or not noticeable, and gastrointestinal side effects like diarrhea or constipation are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OBESITY & OVERWEIGHT are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Huazhong University of Science and Technology

    Wuhan, Hubei, China

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sinopharm Dongfeng General Hospital

    Shiyan, Hubei, China

  • The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture

    Enshi, Hubei, China

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, China

  • Xiangyang No.1 People's Hospital

    Xiangyang, Hubei, China