Could a tweaked stem cell transplant free patients from a lifetime of pills?

NCT ID NCT04678401

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 31 times

Summary

This early-phase study tests a new way to do stem cell transplants for people with aggressive or returning acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). The approach uses specially processed donor cells to reduce the risk of graft-versus-host disease, aiming to eliminate the need for lifelong immunosuppressive drugs. About 30 participants will receive chemotherapy, radiation, and the experimental cell therapy to see if it is safe and effective.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.