Promising heart rhythm fix trial halted early – only 7 patients tested

NCT ID NCT03737929

Terminated Disease control Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to see if combining surgical and catheter ablation (hybrid therapy) works better than standard catheter ablation alone for people with persistent atrial fibrillation. The trial was terminated after enrolling only 7 participants, so no meaningful conclusions can be drawn. The approach remains experimental and unproven.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Hybrid ablation (surgical epicardial ablation combined with percutaneous catheter ablation)
What this could lead to: If it had succeeded, this approach could have offered a more effective treatment for persistent atrial fibrillation, potentially reducing recurrence and the need for repeat procedures.
What could go wrong: The trial was terminated early with only 7 participants, so results are not reliable. Hybrid ablation also carries higher complication risks than catheter ablation alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION

Contacts and locations

Locations

CHU Toulouse, Hôpital Rangueil

Toulouse, 31059, France
Cardiology-rytmology

Paris, France
Cardiology-rytmology service

Toulouse, France

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