New study tests Muscle-Building combo for veterans with HIV and obesity

NCT ID NCT06845046

Recruiting now Disease control Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combination of a special diet, omega-3 and L-carnitine supplements, and resistance exercise can improve muscle quality and reduce fat in veterans with HIV and obesity. The trial will enroll 70 participants and measure changes in muscle density, metabolism, and physical function. It aims to address a common condition called myosteatosis, which can lead to frailty and heart disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: omega-3 fatty acid and L-carnitine supplements, plus a diet high in unsaturated fats and resistance exercise
What this could lead to: If successful, this could point toward a way to improve muscle health and reduce fat in people with HIV, potentially lowering their risk of frailty and heart disease.
What could go wrong: This is a small, early-stage trial with only 70 participants, so results may not apply to everyone. The combination of diet, supplements, and exercise may be hard to stick with long-term.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV OBESITY

Contacts and locations

Locations

Tennessee Valley Healthcare System Nashville Campus, Nashville, TN
RECRUITING

Nashville, Tennessee, 37212-2637, United States

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