Scientists try to personalize heated chemo for stomach cancers
NCT ID NCT04847063
First seen Jun 25, 2026 · Last updated Aug 05, 2026 · Updated 8 times
Summary
This study looks at a treatment called HIPEC, where heated chemotherapy is washed inside the abdomen after surgery to remove tumors. Researchers want to see if lab-grown tumor models can predict how well the chemotherapy works. Sixty adults with cancers that have spread to the abdomen lining will take part. The goal is to find better ways to choose chemotherapy drugs for each person.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hyperthermic intraperitoneal chemotherapy (HIPEC) with drugs like oxaliplatin, cisplatin, mitomycin C, 5-fluorouracil, and sodium thiosulfate
- What this could lead to
- If successful, this could help doctors choose the best chemotherapy drugs for each patient's abdominal tumors, potentially improving treatment outcomes.
- What could go wrong
- This is a very early Phase 1 study with only 60 participants. The lab models may not accurately predict real treatment response, and the approach may not lead to better outcomes for patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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