Scientists try to personalize heated chemo for stomach cancers

NCT ID NCT04847063

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at a treatment called HIPEC, where heated chemotherapy is washed inside the abdomen after surgery to remove tumors. Researchers want to see if lab-grown tumor models can predict how well the chemotherapy works. Sixty adults with cancers that have spread to the abdomen lining will take part. The goal is to find better ways to choose chemotherapy drugs for each person.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hyperthermic intraperitoneal chemotherapy (HIPEC) with drugs like oxaliplatin, cisplatin, mitomycin C, 5-fluorouracil, and sodium thiosulfate

What this could lead to

If successful, this could help doctors choose the best chemotherapy drugs for each patient's abdominal tumors, potentially improving treatment outcomes.

What could go wrong

This is a very early Phase 1 study with only 60 participants. The lab models may not accurately predict real treatment response, and the approach may not lead to better outcomes for patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OVARIAN CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

appendiceal neoplasm appendix cancer colorectal cancer colorectal neoplasm digestive system cancer digestive system neoplasm malignant peritoneal mesothelioma Necrosis ovarian cancer peritoneal carcinomatosis peritoneal mesothelioma peritoneal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••