New breathing method may protect preemie lungs
NCT ID NCT03736707
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a special breathing machine called high-frequency oscillation ventilation (HFOV) works better than standard mechanical ventilation for very premature babies (born at 24 to 31 weeks) who have acute respiratory distress syndrome (ARDS). The goal is to see if HFOV can lower the chance of developing bronchopulmonary dysplasia (BPD), a chronic lung disease common in preemies. About 400 babies will be randomly assigned to one of the two breathing methods, and researchers will track lung health and other outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
High-frequency oscillation ventilation (HFOV) device
What this could lead to
If this works, it could show that HFOV reduces lung damage and bronchopulmonary dysplasia in very preterm babies compared to standard ventilation.
What could go wrong
This is an early-stage trial with 400 infants, and results may not apply to all preterm babies. HFOV also carries risks like air leaks or bleeding in the brain.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Children's Hospital of Chongqing Medical University
RECRUITINGChongqing, Chongqing Municipality, 400042, China
Contact Phone: •••-•••-•••• Email: •••••@•••••