PRETERM

This study tests whether a special breathing machine (high-frequency oscillation) works better than standard machines for very premature babies with lung injury. About 400 babies born between 24 and 31 weeks will be randomly assigned to one of the two machines. The goal is to see…

This study looks at whether starting physiotherapy early can improve movement and development in babies who are at risk for problems like cerebral palsy. About 50 infants from the neonatal unit will be split into two groups: one gets standard care, the other gets extra family-inv…

This study tests two parenting programs for children born very preterm (before 32 weeks) who have behavior problems. One program has seven sessions, and the other uses short online lessons. Both are compared to standard online resources. The goal is to see if these programs impro…

This study tests whether adding a cervical stitch (cerclage) to standard progesterone treatment can prevent preterm birth in women pregnant with twins who have a short cervix. About 260 participants will be randomly assigned to receive either the stitch plus progesterone or proge…

This study looks at whether giving a pacifier to preterm infants at set times (5 minutes before each feeding) or at random times (for 30 minutes anytime) helps them feed more maturely. Researchers will track feeding coordination, weight gain, and hospital stay length. About 62 cl…

This study looks at whether playing a mother's voice during feeding helps preterm babies (born at 28-34 weeks) improve their oxygen levels, heart rate, and feeding skills. About 50 infants will be randomly assigned to hear their mother's voice or not. The goal is to see if this s…

This study tests a medical device called PIMUN to see if it can reduce the time preterm babies spend with low oxygen levels. About 20 infants born before 34 weeks and diagnosed with apnea of prematurity will take part. Each baby will be monitored for 48 hours with the device and …

This study looks at a new wireless device called the Bambi-Belt that tracks heart rate and breathing in extremely premature babies (born before 26 weeks). Researchers want to see if it is easy for nurses to use, comfortable for the baby's skin, and liked by parents. The study wil…

This study tests a new ultrasound technology that can continuously monitor blood flow in the brains of sick and premature infants. Researchers will enroll 180 babies, including healthy preterm and term infants as well as those with conditions like heart defects, infections, or st…

This study looks at whether giving extra arginine (a nutrient) to infants after major bowel surgery or a serious gut infection (NEC) can improve their immune function. Researchers will compare three groups: some get arginine in their IV nutrition, some get it by mouth, and some g…

This UK study follows 90 families of very premature babies (born before 30 weeks) for one year after leaving the hospital. It measures the baby's health, plus the financial, emotional, and social impact on parents and siblings. The goal is to understand the full burden of prematu…