Can a simple stitch help twins stay in the womb longer?

NCT ID NCT07372495

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two approaches to prevent preterm birth in women carrying twins who have a short cervix. One group gets a cervical stitch (cerclage) plus vaginal progesterone, while the other gets progesterone alone. Researchers will track which group has fewer births before 28 weeks, aiming to find the best way to protect these babies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cervical cerclage (a stitch to close the cervix) and vaginal progesterone (hormone medication)

What this could lead to

If it works, this could give doctors a better way to prevent early delivery in twin pregnancies, reducing health risks for babies.

What could go wrong

This is a mid-stage trial with 260 participants, so results may not apply to all. The procedure carries small risks like infection or bleeding, and the combination may not be more effective than progesterone alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bac Ninh 1 Obstetrics and Pediatrics Hospital, Bac Ninh, Vietnam

    NOT_YET_RECRUITING

    Bac Ninh, 220000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Bac Ninh 2 Obstetrics and Pediatrics Hospital, Bac Ninh, Vietnam

    NOT_YET_RECRUITING

    Bac Ninh, 220000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hung Yen Obstetrics and Pediatrics Hospital, Hung Yen, Vietnam

    NOT_YET_RECRUITING

    Hung Yen, 160000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Hospital of Obstetrics and Gynecology

    RECRUITING

    Hanoi, 100000, Vietnam

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • Ninh Binh Obstetrics and Pediatrics Hospital, Ninh Binh, Vietnam

    NOT_YET_RECRUITING

    Ninh Binh, 430000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Quang Ninh Obstetrics and Pediatrics Hospital, Quang Ninh, Vietnam

    NOT_YET_RECRUITING

    Quang Ninh, 200000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••