Immune cells engineered to hunt brain tumors enter first human test

NCT ID NCT03389230

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tests a new immune cell therapy for people with recurrent or treatment-resistant malignant glioma, a type of brain cancer. The treatment uses the patient's own T cells, modified in the lab to recognize and attack cancer cells. The main goal is to find the safest dose and understand side effects in 29 participants.

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Conditions

The condition(s) this trial relates to.

glioblastoma glioma grade III glioma malignant glioma refractory malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States