Blood filters aim to reverse organ failure in septic shock
NCT ID NCT07661303
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether special blood purification devices can help people with septic shock, a life-threatening condition where infection causes organ failure. The trial includes adults aged 18 to 80 with severe septic shock. Depending on their level of endotoxins, patients receive either a device that targets bacterial toxins or one that removes general inflammatory substances. The goal is to see if these treatments improve organ function within 72 hours.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
blood purification devices (Efferon LPS, Toramyxin PMX 20R, Jafron HA 330, CytoSorb)
What this could lead to
If effective, these blood purification methods could offer a new way to reduce organ failure and improve survival in septic shock.
What could go wrong
This is a small pilot study, so results may not be definitive. The devices are compared against each other, not a placebo, and septic shock is complex with many variables.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Bakulev Scientific Center of Cardiovascular Surgery
Moscow, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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City Clinical Hospital No 52, Moscow, Russia
Moscow, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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City clinical hospital named after S. S. Yudin, Moscow City Health
Moscow, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Moscow Multi-disciplinary Clinical Center "Kommunarka"
Moscow, Russia
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National Medical Research Centre for Oncology Rostov-on-Don
Rostov-on-Don, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Petrovsky National Research Centre of Surgery
Moscow, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sklifosovsky Institute of Emergency Care
Moscow, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••