New device aims to plug leaky heart valve in heart failure patients

NCT ID NCT03142152

Recruiting now Disease control Sponsor: Cardiac Dimensions, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a device called the Carillon Mitral Contour System in 300 people with heart failure and a leaky mitral valve. The device is placed in a vein to help the valve close better, reducing blood backflow. The goal is to see if it improves symptoms, walking ability, and reduces hospital stays compared to a sham procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cardiovascular disorder heart disorder heart failure heart valve disorder mitral valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASES FUNCTIONAL MITRAL REGURGITATION HEART DISEASES HEART FAILURE HEART VALVE DISEASES MITRAL VALVE INSUFFICIENCY

Contacts and locations

Locations

AZ Heart Rhythm
WITHDRAWN

Phoenix, Arizona, 85016, United States
Advent Health Hospital
RECRUITING

Orlando, Florida, 32803, United States
Advocate Aurora Research Institute
RECRUITING

Milwaukee, Wisconsin, 53215, United States
Advocate Good Samaritan
RECRUITING

Downers Grove, Illinois, 60515, United States
Albany Medical College,
TERMINATED

Albany, New York, 12208, United States
Allegheny Health Network
RECRUITING

Pittsburgh, Pennsylvania, 15212, United States
Ascension St. Marys Research Institute
TERMINATED

Saginaw, Michigan, 48601, United States
Augusta University Research Institute
TERMINATED

Augusta, Georgia, 30912, United States
Banner Health - Phoenix
RECRUITING

Phoenix, Arizona, 85006, United States
Banner University Tuscon
RECRUITING

Tucson, Arizona, 85724, United States
Baptist Hospital of Miami
TERMINATED

Miami, Florida, 33176, United States
Beth Israel Deaconess
RECRUITING

Boston, Massachusetts, 02215, United States
Cardiovascular Institute South
RECRUITING

Houma, Louisiana, 70360, United States
Carilion Hospital
RECRUITING

Roanoke, Virginia, 24014, United States
Carle Foundation Hospital
TERMINATED

Urbana, Illinois, 61801, United States
Centennial Medical Center
RECRUITING

Nashville, Tennessee, 37203, United States
CentraCare Heart and Vascular
RECRUITING

Saint Cloud, Minnesota, 57584, United States
Centre Hospitalier Universitaire De Lille
WITHDRAWN

Lille, France
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Clinique du Millènaire Montpelier
RECRUITING

Montpellier, France
Community Health Network
RECRUITING

Indianapolis, Indiana, 46256, United States
Deborah Heart & Lung
RECRUITING

Browns Mills, New Jersey, 08015, United States
Delray Medical Center
TERMINATED

Delray Beach, Florida, 33484, United States
Dignity Health Research Institute at Mercy Gilbert and Chandler Regional Medical Centers
RECRUITING

Gilbert, Arizona, 85297, United States
European Interbalkan Medical Center
RECRUITING

Thessaloniki, Greece
Geisinger Medical Center
ACTIVE_NOT_RECRUITING

Danville, Pennsylvania, 17822, United States
HCA Chippenham Medical Center
RECRUITING

Richmond, Virginia, 23225, United States
Hackensack University Medical Center
RECRUITING

Edison, New Jersey, 07601, United States
Harrington Vascular
TERMINATED

Cleveland, Ohio, 44106, United States
Henrico Doctors Hospital
RECRUITING

Henrico, Virginia, 23229, United States
Hospital 12 de Octubre
NOT_YET_RECRUITING

Madrid, Spain
Hospital Clinic de Barcelona
NOT_YET_RECRUITING

Barcelona, Spain
Houston Healthcare Medical Center
RECRUITING

Houston, Texas, 77004, United States
Hôpital Cardiologique Louis Pradel
RECRUITING

Lyon, France
Hôpital Européen Georges-Pompidou
WITHDRAWN

Paris, France
Intermountain Medical Center
TERMINATED

Salt Lake City, Utah, 84111, United States
Johns Hopkins
RECRUITING

Baltimore, Maryland, 21287, United States
Keck School of Medicine of USC
RECRUITING

Los Angeles, California, 90033, United States
Kettering Health Research Institute
RECRUITING

Dayton, Ohio, 45459, United States
Lankenau Institute of Medical Research
RECRUITING

Wynnewood, Pennsylvania, 19096, United States
Lindner Research Center at the Christ Hospital
RECRUITING

Cincinnati, Ohio, 45219, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02145, United States
Medstar
TERMINATED

Washington D.C., District of Columbia, 20010, United States
Memorial Care Hospital
TERMINATED

Long Beach, California, 90806, United States
Methodist Le Bonheur Healthcare
WITHDRAWN

Memphis, Tennessee, 38104, United States
Midwest Cardiovascular Institute (MCI)
RECRUITING

Naperville, Illinois, 60540, United States
North Central Heart-Avera
RECRUITING

Sioux Falls, South Dakota, 57108, United States
Northwell Staten Island
RECRUITING

New York, New York, 11030, United States
Ochsner Health System
RECRUITING

New Orleans, Louisiana, 70121, United States
Oklahoma Heart Institute Hospital
RECRUITING

Tulsa, Oklahoma, 74104, United States
Oregon Health & Science University (OHSU)
RECRUITING

Portland, Oregon, 97225, United States
Palm Beach Gardens Medical
RECRUITING

Palm Beach, Florida, 33410, United States
Penn Medicine Lancaster General Health
RECRUITING

Lancaster, Pennsylvania, 17602, United States
Pole Sante Republique
RECRUITING

Clermont-Ferrand, France
Policinico Umbeto I
NOT_YET_RECRUITING

Roma, Italy
Poznan University of Medical Sciences
RECRUITING

Poznan, Poland, 61-485, Poland
Prairie Heart Institute
TERMINATED

Springfield, Illinois, 62701, United States
Providence Heart Institute
RECRUITING

Portland, Oregon, 97225, United States
Rochester Regional Hospital
RECRUITING

Rochester, New York, 14621, United States
Rush University Medical Center
TERMINATED

Chicago, Illinois, 60612, United States
Saint Francis Hospital,
RECRUITING

Tulsa, Oklahoma, 74136, United States
Scripps Health
RECRUITING

San Diego, California, 92037, United States
Sentara Norfolk General Hospital
WITHDRAWN

Norfolk, Virginia, 23507, United States
South Denver Cardiology
RECRUITING

Littleton, Colorado, 80210, United States
St Boniface Hospital - University of Manitoba
RECRUITING

Winnipeg, Manitoba, Canada
St Elizabeth's Medical Center
RECRUITING

Boston, Massachusetts, 02135, United States
St James University Hospital
RECRUITING

Leeds, United Kingdom
St Michael/Prime Healthcare Services
RECRUITING

Newark, New Jersey, 07102, United States
St. Louis Heart and Vascular
RECRUITING

St Louis, Missouri, 63044, United States
Stanford University
RECRUITING

Redwood City, California, 94063, United States
Tallahassee Research Institute
ACTIVE_NOT_RECRUITING

Tallahassee, Florida, 32308, United States
Tampa General Hospital
RECRUITING

Tampa, Florida, 33606, United States
The Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States
Thomas Jefferson University
WITHDRAWN

Philadelphia, Pennsylvania, 19107, United States
Toronto General Hospital
RECRUITING

Toronto, Ontario, Canada
Tucson Medical Center Health
RECRUITING

Tucson, Arizona, 85712, United States
UCLA Medical Center
RECRUITING

Los Angeles, California, 90095, United States
UPMC Pinnacle Hospitals
RECRUITING

Mechanicsburg, Pennsylvania, 17050, United States
Unity Health Toronto, St Michael's Hospital
RECRUITING

Toronto, Ontario, Canada
University Clinical Hospital of Valladolid
NOT_YET_RECRUITING

Valladolid, Spain
University at Buffalo
RECRUITING

Buffalo, New York, 14203, United States
University of Alberta
WITHDRAWN

Edmonton, Alberta, Canada
University of California- San Francisco
RECRUITING

San Francisco, California, 94143, United States
University of Miami
TERMINATED

Miami, Florida, 33136, United States
University of Michigan
TERMINATED

Ann Arbor, Michigan, 48859, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19014, United States
University of Pittsburgh Medical Center
WITHDRAWN

Pittsburgh, Pennsylvania, 15213, United States
University of Virginia Health System
WITHDRAWN

Charlottesville, Virginia, 22903, United States
Università Federico Naples
RECRUITING

Naples, Italy
Vassar Brothers- Hudson Valley Cardiovascular Practice
RECRUITING

Poughkeepsie, New York, 12601, United States
Wellstar Health System,
TERMINATED

Marietta, Georgia, 30062, United States
William Beaumont Hospital
WITHDRAWN

Royal Oak, Michigan, 48073, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.