12-Minute test could uncover hidden heart failure in leg swelling patients

NCT ID NCT07498868

Not yet recruiting Diagnosis Sponsor: Swansea Bay University Health Board Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study will test a rapid finger-prick blood test for heart failure in 618 people with leg swelling (lymphoedema) who have not been diagnosed with heart failure. The test measures a substance called NT-proBNP and gives results in 12 minutes, compared to the usual lab test that takes days. Researchers want to see if this quick test helps find hidden heart failure earlier, reduces unnecessary doctor visits, and saves money for the health system.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NT-proBNP point-of-care test
What this could lead to: If this works, it could lead to a simple, fast screening test for heart failure in people with leg swelling, catching the condition earlier and reducing hospital visits.
What could go wrong: This is an early observational study, not a treatment trial. The test may not be accurate enough in this specific group, and results may not apply to other clinics or countries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Edema heart failure lymphedema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE HEART FAILURE (FOR EXAMPLE, FLUID OVERLOAD) HEART FAILURE (HF) LYMPHEDEMA LYMPHEDEMA, LOWER LIMB

Contacts and locations

Locations

Swansea Bay Lymphoedema Clinic, Singleton Hospital

Swansea, Swansea, SA2 8QA, United Kingdom

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