Scientists dig into gut bugs to unlock constipation mystery

NCT ID NCT06801184

First seen Jun 25, 2026 · Last updated Jul 28, 2026 · Updated 3 times

Summary

This study looks at the gut bacteria of 40 people with irritable bowel syndrome (IBS) who have constipation and produce high methane. Researchers will collect stool and blood samples to see which bacteria are present and how they change with standard treatment. The goal is to better understand the role of methane-producing microbes in IBS, which could lead to more targeted therapies in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could point toward better diagnostic tools or treatments for constipation-predominant IBS with methane overgrowth.
What could go wrong
This is a small, early observational study with only 40 participants. It does not test a new treatment, so direct benefits are unlikely.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Edouard Herriot

    RECRUITING

    Lyon, 69007, France

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