Scientists dig into gut bugs to unlock constipation mystery

NCT ID NCT06801184

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at the gut bacteria of 40 people with irritable bowel syndrome (IBS) who have constipation and produce high methane. Researchers will collect stool and blood samples to see which bacteria are present and how they change with standard treatment. The goal is to better understand the role of methane-producing microbes in IBS, which could lead to more targeted therapies in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could point toward better diagnostic tools or treatments for constipation-predominant IBS with methane overgrowth.

What could go wrong

This is a small, early observational study with only 40 participants. It does not test a new treatment, so direct benefits are unlikely.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for IRRITABLE BOWEL SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

constipation disorder irritable bowel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Edouard Herriot

    RECRUITING

    Lyon, 69007, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••