Gut bacteria could hold key to better epilepsy treatment

NCT ID NCT07253701

First seen Jan 05, 2026 · Last updated Jun 19, 2026 · Updated 26 times

Summary

This observational study looks at how bacteria in the gut and mouth are linked to epilepsy and whether they affect how well seizure medicines work. Researchers will collect stool, saliva, and blood samples from 1,500 people with newly diagnosed epilepsy and healthy controls. By analyzing these samples, they hope to find patterns that could one day help doctors personalize epilepsy treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Akademiska Sjukhuset

    RECRUITING

    Uppsala, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Drottning Silvias Barnsjukhus

    RECRUITING

    Gothenburg, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Karolinska Universitetssjukhus

    RECRUITING

    Stockholm, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Norrlands universitetssjukhus

    RECRUITING

    Umeå, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Skånes universitetssjukhus

    RECRUITING

    Lund, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitetssjukhuset i Linköping

    RECRUITING

    Linköping, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could help doctors choose the best seizure medicine based on a person's gut bacteria, improving seizure control and reducing side effects.

What could go wrong

This is an observational study, not a treatment trial. It may find no clear links between gut bacteria and epilepsy, or the results may not lead to practical changes in care.

Conditions

The condition(s) this trial relates to.

epilepsy metabolic disease visual epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.