Gut bacteria could hold key to better epilepsy treatment

NCT ID NCT07253701

Recruiting now Knowledge-focused Sponsor: Karolinska Institutet Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study looks at how bacteria in the gut and mouth are linked to epilepsy and whether they affect how well seizure medicines work. Researchers will collect stool, saliva, and blood samples from 1,500 people with newly diagnosed epilepsy and healthy controls. By analyzing these samples, they hope to find patterns that could one day help doctors personalize epilepsy treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help doctors choose the best seizure medicine based on a person's gut bacteria, improving seizure control and reducing side effects.
What could go wrong: This is an observational study, not a treatment trial. It may find no clear links between gut bacteria and epilepsy, or the results may not lead to practical changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

epilepsy metabolic disease visual epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIOMARKER DISCOVERY EPILEPSY METABOLOMICS MICROBIOTA PROTEOMICS

Contacts and locations

Locations

Akademiska Sjukhuset
RECRUITING

Uppsala, Sweden
Drottning Silvias Barnsjukhus
RECRUITING

Gothenburg, Sweden
Karolinska Universitetssjukhus
RECRUITING

Stockholm, Sweden
Norrlands universitetssjukhus
RECRUITING

Umeå, Sweden
Skånes universitetssjukhus
RECRUITING

Lund, Sweden
Universitetssjukhuset i Linköping
RECRUITING

Linköping, Sweden

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