Can a booster shot for the immune system prevent more infections in sepsis survivors?

NCT ID NCT02361528

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called GM-CSF in 166 ICU patients who had severe sepsis or septic shock and a weakened immune system. The goal was to see if the drug could reduce the number of new infections acquired in the ICU. Patients received either GM-CSF or a placebo, and researchers tracked infections and survival up to one year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Sepsis toxic shock syndrome nosocomial infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHM Hopital Nord

    Marseille, 13915, France

  • APHM Hopital de la Timone

    Marseille, 13005, France

  • CHU Amiens Hopital SUD

    Amiens, 80054, France

  • CHU Estaing 1 place Lucie et Raymond Aubrac

    Clermont-Ferrand, 63003, France

  • CHU Gabriel MONTPIED

    Clermont-Ferrand, 63003, France

  • CHU Hopital Nord

    Saint-Etienne, 42055, France

  • CHU Montpellier

    Montpellier, 34295, France

  • CHU de Grenoble- Hopital Michallon

    Grenoble, 38043, France

  • CHU de Grenoble-Hopital Michallon

    Grenoble, 38043, France

  • CHU de Nantes

    Nantes, 44093, France

  • CHU de Nîmes

    Nîmes, 30029, France

  • CHU de Saint-Etienne

    Saint-Etienne, 42055, France

  • CHU la Conception

    Marseille, 13005, France

  • Centre hospitalier Lyon Sud

    Pierre-Bénite, 69495, France

  • Hopital Edouard Herriot

    Lyon, 69003, France

  • Hopital Saint Eloi

    Montpellier, 34295, France

  • Hopital de la Croix Rousse

    Lyon, 69317, France

  • PTMC CHU de Nantes

    Nantes, 44093, France