Gastric bypass showdown: which surgery cures diabetes best?

NCT ID NCT03821636

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two versions of Roux-en-Y gastric bypass surgery to see which one is better at putting type 2 diabetes into remission in severely obese patients. The trial will enroll 396 people with a BMI of 35 or higher and type 2 diabetes. Participants will be randomly assigned to receive either a long alimentary limb or a long biliary limb bypass, and researchers will measure diabetes remission rates along with weight loss and complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Roux-en-Y gastric bypass surgery (two variants: long alimentary limb or long biliary limb)

What this could lead to

If successful, this could show that a specific type of gastric bypass surgery is more effective at putting type 2 diabetes into remission for severely obese patients.

What could go wrong

This is a surgical trial with inherent risks like infection or bowel obstruction. The results may not apply to all patients, and diabetes remission may not be permanent.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ch Boulogne-Sur-Me

    RECRUITING

    Boulogne-sur-Mer, 62321, France

    Contact Phone: •••-•••-••••

  • Ch de Valenciennes

    RECRUITING

    Valenciennes, France

  • Chu Amiens Picardie

    RECRUITING

    Amiens, France

  • Hop Claude Huriez Chu Lille

    RECRUITING

    Lille, 59037, France

    Contact Phone: •••-•••-••••