Study on adding albumin to diuretics for cirrhosis fluid retention halted early

NCT ID NCT04216784

Terminated Disease control Sponsor: Rush University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study aimed to see if adding albumin to the diuretic furosemide helps people with cirrhosis lose excess fluid better than furosemide alone. The trial planned to enroll 21 adults with cirrhosis and fluid buildup. However, it was terminated early due to funding problems, and no patient data was collected.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: furosemide and albumin
What this could lead to: If it had succeeded, this could have shown whether adding albumin to standard diuretics helps remove excess fluid more effectively in people with cirrhosis.
What could go wrong: The trial was terminated early before any data was collected, so no conclusions can be drawn. The combination is already controversial and not proven to work.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Edema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIRRHOSIS, LIVER FLUID OVERLOAD VOLUME OVERLOAD

Contacts and locations

Locations

Rush University Medical Center

Chicago, Illinois, 60612, United States

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