Timing is everything: fluid challenge evaluation in septic shock

NCT ID NCT02116413

Completed Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Nīmes Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 145 patients with septic shock to see if the time when doctors check if a fluid bolus worked changes the results. Patients received 500 ml of fluid over 10 minutes. The study found that some patients who seemed to respond right away were no longer responding 20 minutes later. This helps doctors understand the best time to evaluate treatment effectiveness.

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Conditions

The condition(s) this trial relates to.

toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEPTIC SHOCK

Contacts and locations

Locations

APHM - Hôpital Nord

Marseille, 13915, France
CHRU de Nîmes - Hôpital Universitaire Carémeau

Nîmes, 30029, France
CHU d'Amiens - Hôpital Nord

Amiens, 80054, France
CHU de Besançon - Hôpital Jean Minjoz

Besançon, 25030, France
CHU de Caen - Hôpital Côte de Nacre

Caen, 14033, France
CHU de Clermont Ferrand - Hôpital Estaing

Clermont-Ferrand, 63003, France
CHU de Clermont Ferrand - Hôpital Gabriel-Montpied

Clermont-Ferrand, 63003, France
CHU de Nantes - Hôpital Guillaume et René Laennec

Nantes, 44093, France
CHU de Nice - Hôpital St-Roch

Nice, 06001, France

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