Timing is everything: fluid challenge evaluation in septic shock

NCT ID NCT02116413

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 145 patients with septic shock to see if the time when doctors check if a fluid bolus worked changes the results. Patients received 500 ml of fluid over 10 minutes. The study found that some patients who seemed to respond right away were no longer responding 20 minutes later. This helps doctors understand the best time to evaluate treatment effectiveness.

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Conditions

The condition(s) this trial relates to.

toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHM - Hôpital Nord

    Marseille, 13915, France

  • CHRU de Nîmes - Hôpital Universitaire Carémeau

    Nîmes, 30029, France

  • CHU d'Amiens - Hôpital Nord

    Amiens, 80054, France

  • CHU de Besançon - Hôpital Jean Minjoz

    Besançon, 25030, France

  • CHU de Caen - Hôpital Côte de Nacre

    Caen, 14033, France

  • CHU de Clermont Ferrand - Hôpital Estaing

    Clermont-Ferrand, 63003, France

  • CHU de Clermont Ferrand - Hôpital Gabriel-Montpied

    Clermont-Ferrand, 63003, France

  • CHU de Nantes - Hôpital Guillaume et René Laennec

    Nantes, 44093, France

  • CHU de Nice - Hôpital St-Roch

    Nice, 06001, France