Real-World data on firmonertinib for lung cancer that spread to the brain

NCT ID NCT07239102

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked back at medical records of 300 people with EGFR-positive non-small cell lung cancer that had spread to the brain or spinal cord. All patients were treated with the drug firmonertinib. Researchers analyzed how long the drug controlled brain tumors and explored why some patients stopped responding. The goal is to better understand real-world effectiveness and resistance patterns.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Firmonertinib (oral drug)

What this could lead to

If successful, this analysis could help identify which patients benefit most from firmonertinib and how resistance develops, guiding future treatment strategies.

What could go wrong

This is a retrospective review of past medical records, not a controlled trial. Results may be influenced by incomplete data or patient selection bias.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LEPTOMENINGEAL METASTASIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Meningeal Carcinomatosis metastatic malignant neoplasm in the brain neoplastic meningitis non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Li Xiaoyan

    Beijing, Beijing Municipality, China