Drug duo aims to tackle high blood pressure in obesity

NCT ID NCT07678151

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This study tests whether combining two medications, empagliflozin and finerenone, can lower blood pressure in adults with obesity and stage 1 hypertension. Participants take the drugs or a placebo daily for 12 weeks. The trial also measures effects on kidney function, inflammation, blood sugar, weight, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

empagliflozin and finerenone

What this could lead to

If successful, this combination could offer a new treatment option for people with obesity and high blood pressure, potentially providing better heart and kidney protection than current therapies.

What could go wrong

This is a 12-week trial with 260 participants, so results are preliminary. The combination may cause side effects like high potassium, kidney injury, low blood pressure, or low blood sugar.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Anzhen Hospital, Capital Medical University

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ruyang County People's Hospital

    Luoyang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact