Could tiny stem cell vesicles ease arthritic knees?

NCT ID NCT06466850

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether exosomes—tiny particles from stem cells—can help people with knee osteoarthritis. Twenty adults with mild to moderate knee arthritis will receive two injections of these exosomes into the knee joint. Researchers will measure changes in pain and knee function using a standard questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

exosomes (stem cell-derived vesicles)

What this could lead to

If it works, this could point toward a new non-surgical treatment for knee osteoarthritis that reduces pain and improves joint function.

What could go wrong

This is a very small early trial with only 20 participants, so results may not apply widely. Exosome therapy is still experimental and its long-term safety and effectiveness are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Leila Dehghani

    RECRUITING

    Isfahan, Iran

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••