Exercise may unlock better heart health for diabetes patients

NCT ID NCT04791371

Recruiting now Knowledge-focused Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how exercise affects insulin resistance and heart function in people with type 2 diabetes. Researchers will have 150 participants do 15 weeks of cardiovascular exercise, 3 times a week. They will measure changes in oxygen use and insulin sensitivity to see if exercise helps restore blood flow to muscles and the heart.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cardiovascular exercise
What this could lead to: If successful, this could show that regular exercise improves insulin sensitivity and heart function in people with type 2 diabetes.
What could go wrong: This is an early-stage observational study, not a treatment trial. Results may not apply to all people with diabetes, and exercise adherence may vary.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVERWEIGHT AND OBESITY TYPE 2 DIABETES

Contacts and locations

Locations

University of Colorado
RECRUITING

Aurora, Colorado, 80045, United States
University of Virginia
RECRUITING

Charlottesville, Virginia, 22908, United States

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