Heart check: new stress test may detect chemo damage sooner

NCT ID NCT03505736

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether a stress test combined with a heart MRI can detect early signs of heart damage in premenopausal women treated for breast cancer. The study involved 25 women who had already received treatments like chemotherapy or hormone therapy. Researchers used drugs to stress the heart and then took images to measure blood flow and scarring, aiming to find damage before symptoms appear.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Adenosine, Regadenoson, and Stress Management Therapy
What this could lead to
If successful, this could lead to a way to catch heart damage early in breast cancer patients, helping doctors adjust treatments to protect the heart.
What could go wrong
This is a very small pilot study with only 25 participants, so results may not apply to all patients. It is designed to see if the test works, not to prove it prevents heart problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

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