New study probes Dupilumab's inner workings in asthma patients with obesity

NCT ID NCT05478824

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 27 times

Summary

This study looked at how the drug dupilumab changes gene and protein activity in airway cells from adults with allergic asthma and obesity (BMI 30 or higher). Researchers collected nasal cells from 28 participants to see how dupilumab affects inflammation signals. The goal was to understand why some people respond differently to treatment, not to test a cure or symptom relief directly.

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Contacts and locations

Locations

  • Duke Asthma Allergy and Airway Center

    Durham, North Carolina, 27208, United States

Conditions

Explore the condition pages connected to this study.