Diet over drugs? new study tests if meal replacements can cure diabetes

NCT ID NCT07270068

Recruiting now Disease control Sponsor: Winnie Chee Siew Swee Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a structured lifestyle program, including a total diet replacement phase, can help Malaysian adults with early type 2 diabetes achieve remission. 92 participants will be randomly assigned to either the intensive program or standard care. The goal is to see if more people can stop diabetes medication and maintain healthy blood sugar levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Total Diet Replacement (a meal replacement plan) combined with a structured lifestyle program
What this could lead to: If successful, this could offer a drug-free way to reverse early type 2 diabetes in some people, reducing long-term health complications.
What could go wrong: This is a small, early-stage study (92 people) in one country, so results may not apply widely. The diet is very restrictive and may be hard to maintain long-term.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY TYPE 2 DIABETES

Contacts and locations

Locations

Hospital Putrajaya
RECRUITING

Kuala Lumpur, Putrajaya, 62250, Malaysia
Klinik Kesihatan Seremban
RECRUITING

Seremban, Negeri Sembilam, 70300, Malaysia

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