Front-Back vs. Front-Side: which defibrillator pad placement saves more lives?
NCT ID NCT07818785
First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time
Summary
Emergency medical services teams use defibrillator pads to shock the heart during out-of-hospital cardiac arrest. The VECTORS trial compares two standard pad placements: one with pads on the front and back of the chest, and one with pads on the front and side. Researchers will track whether a pulse returns after the first shock, along with timing and number of shocks, in about 1,500 patients. The goal is to learn whether one placement works better than the other.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- defibrillator electrode pads
- What this could lead to
- If one pad placement proves more effective, it could change emergency response protocols and improve survival from out-of-hospital cardiac arrest.
- What could go wrong
- This is a pragmatic trial comparing two standard approaches, so the difference between them may be small or hard to detect. Results might not apply to all emergency settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,500 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2027
An estimate. Start dates often move.
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Emergency medical services (EMS)-treated non-traumatic out-of-hospital cardiac arrest Exclusion Criteria: * ROSC at EMS arrival (e.g., bystander AED shock with ROSC prior to EMS care) without rearrest during EMS care * Known prisoners * Known pregnant patients * Known pediatric patients (treated under the pediatric algorithm, generally \<15 years) * Known preexisting do-not-resuscitate orders limiting care
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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