New combo aims to outsmart drug resistance in advanced prostate cancer
NCT ID NCT05037500
First seen Nov 12, 2025 · Last updated May 14, 2026 · Updated 27 times
Summary
This early-phase trial tested a combination of two drugs—decitabine/cedazuridine and enzalutamide—in 8 men with metastatic castration-resistant prostate cancer that had stopped responding to standard treatment. The goal was to find a safe dose and see if the combination could reverse or prevent drug resistance. The study was terminated early, so results are limited.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for STAGE IVB PROSTATE CANCER AJCC V8 are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
Conditions
Explore the condition pages connected to this study.