Could a diabetes drug boost success of heart procedure for AFib patients with extra heart fat?

NCT ID NCT07331727

First seen Jan 12, 2026 · Last updated May 04, 2026 · Updated 21 times

Summary

This study tests whether dapagliflozin, a drug typically used for diabetes, can help prevent atrial fibrillation from coming back after a heart ablation procedure. The trial focuses on people with persistent AFib who have increased epicardial adipose tissue (fat around the heart) but do not have diabetes, heart failure, or kidney disease. About 280 participants will receive dapagliflozin or a placebo around the time of their ablation, and researchers will monitor heart rhythm using ECG patches for 3 months.

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Contacts and locations

Locations

  • Shanghai Chest Hospital

    Shanghai, China

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.