Faster heart attack diagnosis put to the test in 28,000-Person trial

NCT ID NCT07727135

First seen Jul 27, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This trial compares two blood-test strategies for diagnosing heart attacks in people with chest pain: the standard approach of testing at arrival and again 3 hours later, versus an accelerated approach testing at arrival and again after just 1 hour. The goal is to see whether the faster method is as safe while allowing patients to leave the hospital sooner. The study involves 28,000 adults at hospitals across Denmark.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
high-sensitivity cardiac troponin blood test
What this could lead to
If the 1-hour strategy proves safe, it could allow faster diagnosis and shorter hospital stays for millions of people with chest pain.
What could go wrong
The 1-hour test might miss some heart attacks that the 3-hour test would catch, potentially increasing risk after discharge.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aalborg University Hospital

    Aalborg, 9000, Denmark

  • Amager & Hvidovre Hospital

    Hvidovre, 2650, Denmark

  • Bispebjerg & Frederiksberg Hospital

    Bispebjerg, 2400, Denmark

  • Central Jutland Regional Hospital (Viborg Hospital & Silkeborg Hospital)

    Viborg, 8800, Denmark

  • Esbjerg og Grindsted Sygehus

    Esbjerg, 6700, Denmark

  • Gødstrup Regional Hospital

    Gødstrup, 7400, Denmark

  • Herlev & Gentofte Hospital

    Herlev, 2730, Denmark

  • Nordsjællands Hospital

    Hillerød, 3400, Denmark

  • Nykøbing Falster County Hospital

    Nykøbing Falster, 4800, Denmark

  • Odense University Hospital

    Odense, 5000, Denmark

  • Svendborg Hospital

    Svendborg, 5700, Denmark

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