Turmeric compound tested as vaginal treatment for cervical precancer
NCT ID NCT04266275
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether curcumin, the active compound in turmeric, can clear HPV and prevent precancerous cervical lesions from returning. About 200 women with low-grade or recently treated high-grade cervical precancer will insert curcumin or placebo capsules vaginally once a week for 20 weeks. After 6 months, they will have a Pap smear and HPV test to see if curcumin helps clear the virus.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
curcumin (from turmeric) vaginal capsules
What this could lead to
If it works, this could offer a low-cost, low-toxicity option to help clear HPV and prevent cervical precancer from coming back.
What could go wrong
This is an early phase 2 trial with only 200 participants. Curcumin is poorly absorbed, and the vaginal route may not work well. The study is not yet recruiting, so results are years away.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Emory University
Atlanta, Georgia, 30303, United States
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Grady Hospital - Ponce De Leon Clinic
Atlanta, Georgia, 30308, United States
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Grady Memorial Hospital
Atlanta, Georgia, 30303, United States