Blood test may spare thousands from unnecessary colonoscopies after diverticulitis

NCT ID NCT06023004

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a blood test that detects tumor DNA can help decide which people with diverticulitis need a colonoscopy to check for colorectal cancer. Currently, almost everyone with diverticulitis is advised to get a colonoscopy, but many are unnecessary. The researchers will compare the blood test results with colonoscopy findings in 220 participants to see if the blood test is accurate enough to guide decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

blood test for circulating tumor DNA (ctDNA)

What this could lead to

If successful, this blood test could help doctors decide who really needs a colonoscopy after diverticulitis, reducing unnecessary procedures and costs.

What could go wrong

This is a small, early-stage study with only 220 participants. The blood test may not be accurate enough to replace colonoscopy, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm diverticulitis diverticulitis of colon

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Herlev Hospital

    Herlev, Capital Region of Denmark, 2730, Denmark

  • Odense University Hospital

    Odense, The Region of Southern Denmark, 5000, Denmark

  • Regional Hospital Horsens

    Horsens, Central Jutland, 8700, Denmark

  • Regional Hospital Randers

    Randers, Central Jutland, 8930, Denmark

  • Regional Hospital Viborg

    Viborg, Central Jutland, 8800, Denmark