CT scans could help tailor ventilator settings for sepsis patients
NCT ID NCT05977153
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looks at two ways of setting a breathing machine (ventilator) for people with sepsis who need help breathing. One method is personalized based on each patient's lung measurements, while the other is a standard approach. Researchers will use CT scans to see how air moves in the lungs and compare which method causes less strain. The goal is to find better ways to protect the lungs during mechanical ventilation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- personalized ventilator settings (PEEP adjustment)
- What this could lead to
- If successful, this could help doctors choose better ventilator settings for sepsis patients, potentially reducing lung damage.
- What could go wrong
- This is a very small, early-phase study with only 7 participants, so results may not apply broadly. It focuses on imaging markers, not direct patient outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Columbia University
New York, New York, 10025, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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