CT scans could help tailor ventilator settings for sepsis patients
NCT ID NCT05977153
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looks at two ways of setting a breathing machine (ventilator) for people with sepsis who need help breathing. One method is personalized based on each patient's lung measurements, while the other is a standard approach. Researchers will use CT scans to see how air moves in the lungs and compare which method causes less strain. The goal is to find better ways to protect the lungs during mechanical ventilation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
personalized ventilator settings (PEEP adjustment)
What this could lead to
If successful, this could help doctors choose better ventilator settings for sepsis patients, potentially reducing lung damage.
What could go wrong
This is a very small, early-phase study with only 7 participants, so results may not apply broadly. It focuses on imaging markers, not direct patient outcomes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Columbia University
New York, New York, 10025, United States