Wireless Lung-Artery sensor could keep heart failure patients out of hospital

NCT ID NCT05934487

Recruiting now Disease control Sponsor: Endotronix, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This trial tests a small sensor placed in the pulmonary artery (the blood vessel from the heart to the lungs) that wirelessly sends daily pressure readings to doctors. The goal is to help people with moderate heart failure (NYHA Class II or III) manage their condition at home and avoid hospital stays. About 1,750 participants will be randomly assigned to get the sensor or standard care, and researchers will track heart failure events and deaths over up to 24 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cordella™ Pulmonary Artery Sensor System (implantable device)
What this could lead to: If successful, this device could help heart failure patients manage their condition at home, reducing hospital visits and improving quality of life.
What could go wrong: This is an early-stage trial with 1750 participants; the device requires a procedure to implant, which carries risks like infection or sensor failure. It may not significantly reduce hospitalizations.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder heart disorder heart failure mild heart failure moderate heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE HEART FAILURE NYHA CLASS II HEART FAILURE NYHA CLASS III

Contacts and locations

Locations

AZORG Aalst
ACTIVE_NOT_RECRUITING

Aalst, 9300, Belgium
Advocate Aurora St. Luke's
RECRUITING

Milwaukee, Wisconsin, 53215, United States
Advocate Health System
RECRUITING

Downers Grove, Illinois, 60515, United States
Ascension Providence Hospital Cardiology - Heart Cardiology
RECRUITING

Howell, Michigan, 48843, United States
Ascension Sacred Heart
RECRUITING

Pensacola, Florida, 32504, United States
Ascension St. Vincent's
RECRUITING

Indianapolis, Indiana, 46260, United States
Austin Heart
RECRUITING

Austin, Texas, 78756, United States
Baptist Health South Florida
RECRUITING

Miami, Florida, 33176, United States
Baylor - Temple
RECRUITING

Temple, Texas, 76508, United States
Baylor Scott & White -Dallas
RECRUITING

Dallas, Texas, 75246, United States
Baylor/Texas Heart
RECRUITING

Houston, Texas, 77030, United States
Boston Medical Center Corporation
NOT_YET_RECRUITING

Boston, Massachusetts, 02118, United States
Centra Care Heart Center
RECRUITING

Saint Cloud, Minnesota, 56303, United States
Duke University
RECRUITING

Durham, North Carolina, 27710, United States
Heart Care Centers of Illinois (HCCI)
RECRUITING

Palos Park, Illinois, 60464, United States
Lenox Hill/ Northwell Health
RECRUITING

New York, New York, 10075, United States
MedStar
RECRUITING

Baltimore, Maryland, 21239, United States
Medical City Healthcare Dallas
RECRUITING

Dallas, Texas, 75240, United States
Medical University of South Carolina (MUSC)
RECRUITING

Charleston, South Carolina, 29425, United States
Methodist San Antonio
RECRUITING

San Antonio, Texas, 78229, United States
Mount Sinai
RECRUITING

New York, New York, 10029, United States
Mount Sinai West
RECRUITING

New York, New York, 10019, United States
Oregon Health Science Portland
RECRUITING

Portland, Oregon, 97239, United States
PRISMA Health- Upstate
RECRUITING

Greenville, South Carolina, 29605, United States
Penn State Health
RECRUITING

Hershey, Pennsylvania, 17033, United States
Piedmont
RECRUITING

Atlanta, Georgia, 30309, United States
Providence Everett
RECRUITING

Everett, Washington, 98201, United States
Providence St. Vincent's - Portland
RECRUITING

Portland, Oregon, 97225, United States
Sanford
RECRUITING

Sioux Falls, South Dakota, 57105, United States
St. Joseph's Hospital and Medical Center
RECRUITING

Phoenix, Arizona, 85013, United States
St. Lukes/ Mid-American Heart Institute
RECRUITING

Kansas City, Missouri, 64111, United States
Stony Brook University Med Center
RECRUITING

Stony Brook, New York, 11794, United States
The Christ Hospital- Cincinnati
RECRUITING

Cincinnati, Ohio, 45219, United States
Tufts Medical Center
RECRUITING

Boston, Massachusetts, 02111, United States
UCSF Medical Center
RECRUITING

San Francisco, California, 94143, United States
UNC Medical Center
RECRUITING

Durham, North Carolina, 27703, United States
UPMC
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
USC
RECRUITING

Los Angeles, California, 90033, United States
UZ Brussel
ACTIVE_NOT_RECRUITING

Brussels, Belgium
University Hospital (Cleveland)
RECRUITING

Cleveland, Ohio, 44106, United States
University Hospital Galway
ACTIVE_NOT_RECRUITING

Galway, Ireland
University of Cincinnati
RECRUITING

Cincinnati, Ohio, 45267, United States
University of Kansas Medical Center (KUMC)
RECRUITING

Kansas City, Kansas, 66160, United States
University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States
University of Vermont
RECRUITING

Burlington, Vermont, 05401, United States
University of Wisconsin
RECRUITING

Madison, Wisconsin, 53792, United States
Vanderbilt
RECRUITING

Nashville, Tennessee, 37232, United States
West Virginia University
RECRUITING

Morgantown, West Virginia, 26506, United States

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