Can induced hypothermia save more lives after In-Hospital cardiac arrest?
NCT ID NCT07086703
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether cooling patients to 33°C (therapeutic hypothermia) improves survival and brain function compared to keeping them at normal body temperature after an in-hospital cardiac arrest. About 788 comatose adults who had a cardiac arrest in the hospital will be randomly assigned to either cooling or controlled normothermia. The main goal is to see if more patients have a good neurological outcome at 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Induced hypothermia (cooling to 33°C)
What this could lead to
If cooling works, it could become a standard treatment to improve survival and brain recovery after in-hospital cardiac arrest.
What could go wrong
This is a large but early-stage trial, and previous studies have shown mixed results. Cooling may not improve outcomes and could cause side effects like infection or heart rhythm problems.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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APHM - Hôpital Nord
Marseille, 13015, France
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APHP - Hôpital Ambroise Paré
Paris, 92200, France
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APHP- Hôpital Cochin
Paris, 75679 cedex 14, France
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APHP-Hôpital Saint-Antoine
Paris, 75517, France
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CH Brocéliande Atlantique
Vannes, 56017 cedex 1, France
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CH Dubois Brive
Brive-la-Gaillarde, 19312 cedex, France
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CH Public du Cotentin
Cherbourg, 50102, France
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CH d'Angoulême
Angoulême, 16000, France
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CH de Roanne
Roanne, France
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CH de Rodez
Rodez, 12027, France
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CHD Vendée
La Roche-sur-Yon, 85025 Cedex, France
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CHR d'Orléans
Orléans, 45100, France
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CHRU de Strasbourg
Strasbourg, 67091 cedex, France
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CHRU de Tours
Tours, 37044 Cedex 9, France
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CHRU- Hôpital Roger Salengro
Lille, 59307 cedex, France
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CHU Bocage
Dijon, 77908, France
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CHU Charleroi
Charleroi, Belgium
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CHU Clermont-Ferrand
Clermont-Ferrand, 63003 cedex 1, France
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CHU Dupuytren
Limoges, 87042 Cedex 1, France
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CHU Les Abymes
Pointe-à-Pitre, La Guadeloupe, 97110, Guadeloupe
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CHU de Caen
Caen, 14033, France
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CHU de Nantes
Nantes, France
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Clinique Saint-PIerre
Ottignies, Belgium
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Hôpital André Mignot
Le Chesnay, 78150, France
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Hôpital Edouard Herriot
Lyon, 69437, France
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Hôpital Erasme
Brussels, Belgium
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Hôpital Privé Jacques Cartier
Massy, 91300, France
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Hôpital Sainte-Musse
Toulon, 83100, France
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Hôpital Simone Veil
Cannes, 06414 cedex, France
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Hôpital Universitaire de Bruxelles
Jette, Belgium
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Hôpital Universitaire de Gand
Ghent, Belgium
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Hôpital de l'Archet
Nice, 06200, France
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