Could surgery after chemo double survival for advanced stomach cancer?
NCT ID NCT07241715
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether surgery to remove stomach cancer that has spread to the abdomen can help people live longer when done after chemotherapy. About 300 adults whose cancer responded well to initial treatment will be randomly assigned to either have surgery plus more therapy or continue therapy alone. The main goal is to see if surgery improves overall survival and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Conversion surgery (surgery to remove the stomach tumor and cancer spread) plus systemic therapy (chemotherapy, targeted therapy, immunotherapy) with or without chemotherapy given directly into the abdomen
What this could lead to
If it works, this could show that surgery after chemotherapy helps people with advanced stomach cancer live longer and have a better quality of life.
What could go wrong
This is a mid-stage trial, so results are not yet proven. Surgery in this setting carries risks like infection or complications, and the cancer may still come back.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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National University Hospital
Singapore, Singapore