New spray chemotherapy trial targets Stomach-Lining cancer
NCT ID NCT07349043
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tests a new way to deliver chemotherapy for colorectal cancer that has spread to the lining of the abdomen. Doctors use a spray (PIPAC) to send the drugs mitomycin or raltitrexed directly into the belly during a keyhole surgery. The main goal is to find a safe dose and check for side effects in 42 adults who are also getting standard treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- mitomycin or raltitrexed delivered as a pressurized aerosol into the abdomen
- What this could lead to
- If this works, it could offer a new way to control colorectal cancer that has spread to the abdomen, potentially improving survival when combined with standard chemotherapy.
- What could go wrong
- This is a very early Phase 1 trial with only 42 people, focused on finding a safe dose, not proving it works. The treatment may cause side effects like nausea, fatigue, or pain, and it is unclear if it will actually help patients live longer.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Second Affiliated Hospital, Zhejiang University School of Medicine 88 Jiefang Road Hangzhou, Zhejiang 310009, China
RECRUITINGHangzhou, Other (Non U.s.), 310000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a four-pronged attack shrink liver tumors enough for surgery?
- Can a Two-Pronged antibody boost chemo against Hard-to-Treat colorectal cancer?
- New drug cocktail aims to shrink Hard-to-Treat colorectal tumors
- Real-World data on colorectal cancer: what happens to patients over time?
- Engineered immune cells take on Hard-to-Treat colorectal cancer