Which weight loss surgery works best? major trial launches

NCT ID NCT04915014

Ongoing Disease control Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two weight loss surgeries for people with severe obesity: sleeve gastrectomy with transit bipartition (SG+TB) and Roux-en-Y gastric bypass (RYGB). About 320 participants will be followed for two years to see which surgery leads to greater weight loss and fewer side effects. The goal is to find the best surgical option for long-term weight control and health improvement.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Malnutrition metabolic syndrome X morbid obesity type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEVERE OBESITY

Contacts and locations

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Locations

AP-HP Hôpital Bichat

Paris, France
AP-HP Hôpital Georges Pompidou

Paris, France
CHU Orléans

Orléans, France
CHU de Lyon

Lyon, France
CHU de Nancy

Vandœuvre-lès-Nancy, France
CHU de Nantes

Nantes, France
CHU de Poitiers

Poitiers, France
Hop Claude Huriez Chu Lille

Lille, 59037, France