Which Weight-Loss surgery works best? major trial launched

NCT ID NCT04915014

First seen Feb 15, 2026 · Last updated May 16, 2026 · Updated 13 times

Summary

This study compares two weight-loss surgeries for people with severe obesity: sleeve gastrectomy with transit bipartition (SG+TB) and Roux-en-Y gastric bypass (RYGB). About 320 adults will be followed for two years to see which surgery leads to more weight loss and fewer side effects. The goal is to find the best surgical option for long-term weight control and health improvement.

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Contacts and locations

Locations

  • AP-HP Hôpital Bichat

    Paris, France

  • AP-HP Hôpital Georges Pompidou

    Paris, France

  • CHU Orléans

    Orléans, France

  • CHU de Lyon

    Lyon, France

  • CHU de Nancy

    Vandœuvre-lès-Nancy, France

  • CHU de Nantes

    Nantes, France

  • CHU de Poitiers

    Poitiers, France

  • Hop Claude Huriez Chu Lille

    Lille, 59037, France

Conditions

Explore the condition pages connected to this study.