Can a new stomach surgery tame acid reflux without hiding cancer risks?

NCT ID NCT07768202

NEW Ongoing Disease control Sponsor: Victor Dib Institute Source: ClinicalTrials.gov ↗

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This trial tests whether a newer surgical technique, which combines sleeve gastrectomy with a rerouting of the digestive tract, can control acid reflux as well as the standard gastric bypass in adults with obesity. The new approach aims to keep the entire digestive tract visible for future endoscopic exams, unlike the bypass. Participants are randomly assigned to one of the two procedures, and the study tracks reflux symptoms, weight loss, and metabolic changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sleeve gastrectomy with Roux-en-Y antrum-jejunal anastomosis (AJYR+SG) versus Roux-en-Y gastric bypass
What this could lead to: If successful, this new surgical technique could offer a way to control acid reflux as effectively as gastric bypass while keeping the digestive tract fully accessible for future cancer screening.
What could go wrong: This is a relatively small, early-stage surgical trial, and the new procedure may not control reflux as well as expected or could carry its own risks. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease morbid obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROESOPHAGEAL REFLUX (GERD) OBESITY, MORBID

Contacts and locations

Locations

Victor Dib Institute

Manaus, Amazonas, 69020-210, Brazil

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