Sleep apnea combo therapy shows promise in early trial
NCT ID NCT07577661
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining a nerve-stimulating implant with two medications (atomoxetine and oxybutynin) can improve breathing during sleep more than either treatment alone. Twenty-four adults with obstructive sleep apnea who already have the implant will try each combination in random order. The goal is to see if the combo reduces breathing pauses better than the implant or medication by itself.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hypoglossal nerve stimulation device and atomoxetine plus oxybutynin
What this could lead to
If it works, this could point toward a more effective treatment for obstructive sleep apnea that combines a device and medication.
What could go wrong
This is a very small, early-phase trial with only 24 people. The combination may not work better than either treatment alone, and the medications can cause side effects like dry mouth or dizziness.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OBSTRUCTIVE SLEEP APNEA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••