Can a common gout pill ease the aftermath of a blood clot?

NCT ID NCT06440694

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing whether a low dose of colchicine, a drug usually used for gout, can reduce the risk of post-thrombotic syndrome (PTS) after a deep vein thrombosis (DVT) in the leg. PTS can cause chronic pain, swelling, and skin changes. The trial will enroll 150 adults with a first DVT, giving them either colchicine or a placebo daily for 180 days. The main goal is to see if a larger study is feasible, not yet to prove the drug works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Colchicine (0.5 mg daily for 180 days)

What this could lead to

If it works, this could point toward a simple, affordable way to prevent long-term leg pain and swelling after a blood clot.

What could go wrong

This is a small pilot trial focused on feasibility, not yet on proving effectiveness. Colchicine can cause diarrhea and other side effects, and it may not reduce post-thrombotic syndrome.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Inflammation Postthrombotic Syndrome venous thromboembolism post-thrombotic syndrome prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre de recherche du Centre hospitalier de l'Université de Montréal

    RECRUITING

    Montreal, Quebec, H2X 0A9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Ottawa Hospital General Campus

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

    Contact

    Contact Email: •••••@•••••

  • The Sir Mortimer B. Davis Jewish General Hospital

    NOT_YET_RECRUITING

    Montreal, Quebec, H3T 1E2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact