Can a common gout pill ease the aftermath of a blood clot?

NCT ID NCT06440694

Recruiting now Disease control Sponsor: Ottawa Hospital Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This pilot study is testing whether a low dose of colchicine, a drug usually used for gout, can reduce the risk of post-thrombotic syndrome (PTS) after a deep vein thrombosis (DVT) in the leg. PTS can cause chronic pain, swelling, and skin changes. The trial will enroll 150 adults with a first DVT, giving them either colchicine or a placebo daily for 180 days. The main goal is to see if a larger study is feasible, not yet to prove the drug works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Colchicine (0.5 mg daily for 180 days)
What this could lead to: If it works, this could point toward a simple, affordable way to prevent long-term leg pain and swelling after a blood clot.
What could go wrong: This is a small pilot trial focused on feasibility, not yet on proving effectiveness. Colchicine can cause diarrhea and other side effects, and it may not reduce post-thrombotic syndrome.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for VENOUS THROMBOEMBOLISM are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Inflammation Postthrombotic Syndrome venous thromboembolism post-thrombotic syndrome prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VENOUS THROMBOEMBOLISM

Contacts and locations

Locations

Centre de recherche du Centre hospitalier de l'Université de Montréal
RECRUITING

Montreal, Quebec, H2X 0A9, Canada
The Ottawa Hospital General Campus
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada
The Sir Mortimer B. Davis Jewish General Hospital
NOT_YET_RECRUITING

Montreal, Quebec, H3T 1E2, Canada
Windsor Regional Hospital
RECRUITING

Windsor, Ontario, N8W2X3, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.