Heart attack drug trial halted early: Colchicine's nerve protection unproven

NCT ID NCT04420624

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether the anti-inflammatory drug colchicine could prevent nerve damage in the heart after a heart attack. About 54 adults who had a first heart attack and underwent artery-opening treatment were given colchicine or a placebo for one month. The trial was terminated early, so it is unclear if colchicine provides any benefit for this purpose.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

colchicine

What this could lead to

If it had worked, this could point toward a way to reduce heart nerve damage after a heart attack.

What could go wrong

The study was terminated early with only 54 participants, so we don't have enough data to know if colchicine helps. It was also a small, early-phase trial.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MYOCARDIAL INFARCTION, ACUTE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute myocardial infarction heart failure myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UH Montpellier

    Montpellier, 34090, France